Requests for WGRC germ plasm and reprints.

E-mail requests for WGRC germ plasm, germ plasm releases, and publication reprints can now be made to wgrc@ksu.edu.

Update: improved germ plasm lines with pest resistance genes from Aegilops tauschii.

D.L. Wilson, B.S. Gill, and W.J. Raupp.

In previous research, Ae. tauschii has proven to be an excellent source for producing pest resistant germ plasm lines (see list of released germ plasm lines in Table 1). Current data indicate Ae. tauschii will continue to be a valuable source of resistance for these and new pests. Several research groups are transferring genetic resistances from Ae. tauschii into bread wheat. The coordination of this research will amplify this effort by avoiding duplication of effort in the evaluation of the collection, stimulating additional research by providing information on the resistance spectrum of each accession, and raising the awareness of the individual investigator for potential variability in their segregating populations.

Table 1. Germ plasm releases from the Wheat Genetics Resource Center with pest resistance from

Aegilops tauschii.

____________________________________________________________________________________________

Germ plasm Resistance 1 Germ plasm Resistance 1

____________________________________________________________________________________________

KS85WGRC01 H22 KS92WGRC15 leaf rust

KS86WGRC02 leaf rust KS92WGRC16 Lr43

KS89WGRC03 Hessian fly KS92WGRC21 powdery mildew, WSBMV, WSSMV

KS89WGRC04 H23, WSBMV, greenbug KS92WGRC22 powdery mildew, WSBMV, WSSMV

KS89WGRC06 H24 KS93WGRC26 H26

KS89WGRC07 leaf rust KS95WGRC33 Septoria leaf blotch

KS90WGRC10 Lr41 KS96WGRC39 tan spot

KS91WGRC11 Lr42, WSBMV, WSSMV KS96WGRC40 wheat curl mite, Septoria nodorum

KS91WGRC12 leaf rust, adult

____________________________________________________________________________________________

1 WSBMV = wheat soilborne mosaic virus; WSSMV = wheat spindle streak mosaic virus.

Sex, segregation, and recombination in Ae. tauschii.

J.D. Faris, B.A. Laddomada, E.V. Boiko, K.S. Gill, and B.S. Gill.

Beginning in 1989, we have been developing a genetic linkage map of the D-genome diploid Ae. tauschii using an F2 population of 56 plants from a cross of varieties meyerii (TA1691) and typica (TA1704). We previously noted that all five loci of the rudimentary 5D-linkage map from our laboratory (Genome 32:724-732, 1989) deviated from the expected 1:2:1 ratio. Major segregation-distortion loci were detected on chromosome arms 1DL, 3DL, 4DS, and 7DS in addition to 5DL. Segregation distortion was caused by the deficiency of TA1704 homozygotes in all cases except 7DS, where individuals for TA1691 homozygous alleles were deficient. We have created reciprocal backcross populations of almost 200 individuals based on male and female meiosis. We can now confirm that 5DL deviant loci show normal segregation through female gametes, but TA1691 alleles are preferentially transmitted (at a 90 % or higher frequency) through the male gametes. Similar analysis in underway for the alleles associated with other segregation distortion loci.

Publications.

Badaeva ED, Friebe B, and Gill BS. 1996. Genome differentiation in Aegilops. 1. Distribution of highly repetitive DNA sequences on chromosomes of diploid species. Genome 39:293-306.

Badaeva ED, Friebe B, and Gill BS. 1996. Genome differentiation in Aegilops. 2. Physical mapping of 5S and 18S-26S ribosomal RNA gene families in diploid species. Genome 39:1150-1158.

Brown-Guedira GL, Gill BS, Bockus WW, Cox TS, Hatchett JH, Leath S, Peterson CJ, Thomas JB, and Zwer PK. 1996. Evaluation of a collection of wild timopheevi wheat for resistance to disease and arthropod pests. Plant Dis 80:928-933.

Brown-Guedira GL, Gill BS, Cox TS, and Leath S. 1997. Transfer of disease resistance genes from Triticum araraticum to common wheat. Plant Breed (In press).

Brown-Guedira GL, Badaeva ED, Gill BS, and Cox TS. 1996. Chromosome substitutions of Triticum timopheevii in common wheat and some observations of the evolution of polyploid wheat species. Theor Appl Genet 93:1291-1298.

Cox TS, Bockus WW, Gill BS, Sears RG, Heer WF, and Long JH. 1996. Notice of release of KS95WGRC33 hard red winter wheat germplasm resistant to Septoria leaf blotch. Fall Cereals Conf, 3-4 August, 1995, Manhattan, KS. p.8.

Cox TS, Gill BS, Sears RG, Harvey TL, Hatchett JH, Hulbert SH, Brown-Guedira, GL, Faris, JA, Friebe B, Gill KS, Knackstedt MA, Raupp WJ, Thiry D, and Van Metteren ND. 1996. Research summary. Ann Wheat Newslet 42: 250-261.

Endo TR and Gill BS. 1996. The deletion stocks of common wheat. J Hered 87:295-307.

Friebe B, Badaeva ED, Hammer K, and Gill BS. 1996. Standard karyotypes of Aegilops uniaristata, Ae. mutica, Ae. comosa ssp. comosa and heldreichii (Poaceae). Pl Syst Evol 202:199-210.

Friebe B and Cortez F. 1996. Sister chromatid exchange and replication banding. In: Plant Chromosomes. Laboratory Methods (Fukui K and Nakayama S eds). CRC Press, Boca Raton, FL. pp. 171-186.

Friebe B, Endo TR, and Gill BS. 1996. Chromosome banding methods. In: Plant Chromosomes. Laboratory Methods (Fukui K and Nakayama S eds). CRC Press, Boca Raton, FL. pp. 123-153.

Friebe B and Gill BS. 1996. Chromosome banding and genome analysis in diploid and cultivated polyploid wheats. In: Methods of Genome Analysis in Plants (Jauhar PP ed). CRC Press, Boca Raton, FL. pp. 39-59.

Friebe B, Gill KS, Tuleen NA, and Gill BS. 1996. Transfer of wheat streak mosaic virus resistance from Agropyron intermedium into wheat. Crop Sci 36:857-861.

Friebe B, Tuleen NA, Badaeva ED, and Gill BS. 1996. Cytogenetic identification of Triticum peregrinum chromosomes added to common wheat. Genome 39:272-276.

Friebe B, Jellen EN, and Gill BS. 1996. Verification of the identity of the Chinese Spring ditelosomic stocks Dt7DS and Dt7DL. Wheat Inf Serv 83:31-32.

Friebe B, Jiang J, Raupp WJ, McIntosh RA, and Gill BS. 1996. Characterization of wheat-alien translocations conferring resistance to diseases and pests: current status. Euphytica 91:59-87.

Gill BS. 1996. The molecular cytogenetic analysis of economically important traits in plants. In: Kew Chromosome Conf IV (Brandham PE and Bennett MD eds). Royal Botanic Gardens, Kew, United Kingdom. pp. 47-53.

Gill BS, Gill KS, Friebe B, and Endo TR. 1996. Expanding genetic maps: reevaluation of the relationship between chiasmata and crossovers. In: Chromosomes Today Volume 12 (Henriques-Gil N, Parker JS, and Puertas MJ eds). pp. 283-300.

Gill KS and Gill BS. 1996. A PCR-based screening assay of Ph1, the chromosome pairing regulator gene of wheat. Crop Sci 36:719-722.

Gill KS, Gill BS, Endo TR, and Boyko EV. 1996. Identification and high-density mapping of gene-rich regions in chromosome group 5 of wheat. Genetics 143:1001-1012.

Gill KS, Gill BS, Endo TR, and Taylor T. 1996. Identification and high-density mapping of gene-rich regions in chromosome group 1 of wheat. Genetics 144:1883-1891.

Gill KS, Nasuda S, and Gill BS. 1996. Isolation, cloning, and gel blot analysis of high molecular weight DNA. BioTechniques 21:572-576.

Hohmann U, Badaeva K, Busch W, Friebe B, and Gill BS. 1996. Molecular cytogenetic analysis of Agropyron chromatin specifying resistance to barley yellow dwarf virus in wheat. Genome 39:336-347.

Hussein T, Bowden RL, Gill BS, and Cox TS. 1996. Performance of four new leaf rust resistance genes from Triticum tauschii and T. monococcum. Phytopath 86:S24 (Abstract).

Jellen EN and Gill BS. 1996. C-banding variation in the Moroccan oat species Avena agadiriana (2n = 4x = 28). Theor Appl Gene t 92:726-732.

Jellen EN, Gill BS, Rines HW, Fox SL, Wilson WA, and McMullen MS. 1996. Translocations in current and ancestral spring and winter oat accessions. Agron Abstr.

Jiang J, Nasuda S, Dong F, Scherrer CW, Wing RA, Gill BS, and Ward DC. 1996. A conserved repetitive DNA element located in the centromere of cereal chromosomes. Proc Natl Acad Sci USA 93:14210-14213.

Jiang J, Hulbert SH, Gill BS, and Ward DC. 1996. Interphase fluorescence in situ hybridization mapping: a physical mapping strategy for plant species with large complex genomes. Molec Gen Genet 252:497-502.

Kawahara T, Badaeva ED, Badaev NS, and Gill BS. 1996. Spontaneous translocations in Triticum araraticum Jakubz. Wheat Inf Serv 83:7-14.

Zhang J, Friebe B, Raupp WJ, Harrison SA, and Gill BS. 1996. Wheat embryogenesis and haploid embryo production in wheat x maize hybrids. Euphytica 90:315-324.

Jiang J and Gill BS. 1996. Current status and potential of fluorescence in situ hybridization in plant genome mapping. In: Genome Mapping in Plants (Paterson AH ed). R.G. Landes Co. pp.127-135.

Raupp WJ. 1996. Annual Wheat Newsletter, Vol. 42. 463 pp.

Raupp WJ, Wilson DL, Friebe B, and Gill BS. 1996. Current status of the Wheat Genetics Resource Center gene bank: Investigating the flow of germ plasm. Agron Abstr.

Sears RG, Gill BS, Cox TS, and Paulsen GM. 1996. If Turkey Red had been Turkey White. Agron Abstr.

Wilson DL, Cox TS, Gill BS, Raupp WJ, Hatchett JH, Harvey TL, and Thomas JB. 1996. Pest resistance and agronomic evaluations of Aegilops tauschii. Agron Abstr.


U.S. GRAIN MARKETING AND PRODUCTION RESEARCH CENTER

U.S. Grain Marketing Research Laboratory, USDA, Agricultural Research Service, Manhattan, KS 66502, USA.


O.K. Chung, G.L. Lookhart, J.L. Steele, S.R. Bean, I.Y. Zayas, C.R. Martin, J.B. Ohm, D.B. Bechtel, L.M. Seitz, J.D. Wilson, J.D. Hubbard, J.M. Downing, C.S. Chang, D.W. Hagstrum, K.J. Kramer, D.B. Sauer, W.J. Jun, H.S. Park, S.H. Park, J.E. Baker, P.W. Flinn, T.D. Morgan, W.H. McGaughey, B.W. Seabourn, Y.S. Kim, M.D. Shogren, and D.E. Koeltzow.

New methods help to solve the gluten puzzle.

A wide range of methods for characterizing gluten proteins were discussed at the Gluten Workshop this year. These methods included: solubility of gluten proteins and their relationships to quality; high-performance capillary zone electrophoresis (CZE) for unique separations of gluten proteins and fractions, HPLC separations to purify and characterize gluten proteins; the use of antibodies to identify specific proteins; electrophoresis for studying protein fractions at the individual protein and gene levels; MALDI-TOF for accurate mass analysis of proteins and sequences of peptides; biophysical studies using NMR, atomic-force spectroscopy, and FT-IR to study the structures and interactions of gluten proteins; and the combined use of genetics with all of the above methods to study not only diploids, but hexaploid bread wheats as well. Because most of those methods will be discussed in detail, this presentation will begin with an overview of the newest CZE methods and end with a broad discussion of the other methods that will include some crystal-ball gazing into how each of the methods uncovers some portion of the puzzle that illustrates gluten protein structure on a molecular level and an understanding of end-use quality on a practical scale. (Presented at the Gluten Workshop, Sydney, Australia)

Ultrastructure of consecutively extracted and flocculated gliadins and glutenins.

Gliadin and glutenin are characterized by specific ultrastructures, which depend on variety and separation conditions. Gliadins of the Israeli spring wheat Ariel extracted with 80 % ethanol appeared as spherical bodies within an amorphous perforated matrix. The gliadins of a commercial sample of U.S. hard red winter wheat were deposited in bundles of bodies of concentric membrane-like units during water dialysis and they tended to separate when heated at 120 C. Acetic-acid-extracted glutenins heated at 120 C appeared as amorphous, compact agglomerated particles beside dispersed aggregates, fibril-like patterns, and oil-like bodies. The extracted glutenins, which were dialyzed in water, appeared as dispersed or aggregated particles beside oil-like bodies embedded in and/or encapsulated by coagulated protein. Differences were found in high-performance capillary electrophoresis patterns of both gliadins and glutenins between the Israeli spring wheat Ariel and the good baking-quality U.S. HRWW Karl 92. The structural differences are results of different proteins and differences in the physicochemical properties of the proteins.

Identification of wheat lines containing the T1AL-1RS and T1BL-1RS translocations by high-performance capillary electrophoresis.

High-performance capillary electrophoresis (HPCE) was used to analyze grain proteins from wheat cultivars with the T1AL-1RS or T1BL-1RS wheat-rye chromosomal translocations. Chromosome specific patterns were observed among released cultivars and experimental lines. The method was verified by analyzing protein extracts of the heterogeneous cultivars Nekota and Rawhide and their homogeneous, homozygous non-1RS progeny. The purified T1AL-1RS and T1BL-1RS progenies were derived from Nekota and Rawhide, respectively. HPCE provides a rapid and efficient method for detection of flour or grain derived from T1AL-1RS and T1BL-1RS wheats and can differentiate the two types of translocations.

Separation of wheat proteins by two-dimensional reversed-phase high performance liquid chromatography plus free-zone capillary electrophoresis.

Gliadins and glutenins from four wheat cultivars were separated by a new two-dimensional technique. Protein extracts were separated by RP-HPLC as the first dimension with each 30-second interval collected separately. Those fractions were separated by free-zone capillary electrophoresis (FZCE) for the second dimension. Data were combined into two dimensional (2-D) surface contour plots similar to traditional gel electrophoresis 2-D maps. C8 and C18 columns were used in the first dimension to separate gliadins and glutenins, respectively. Uncoated fused silica capillaries (`27 cm x 25 m' i.d.) were used for the second dimension FZCE separations. Differences in the 2-D maps of both gliadin and glutenin fractions were found between pairs of both closely related and sister lines that varied in quality.

High-performance capillary electrophoresis: an overview of a new method to characterize gluten proteins.

HPCE is a relatively new method for separating cereal proteins. The inherent advantages of HPCE are low mass requirements, fast separations, automation, and quantitative determinations via UV-detection through the capillary. HPCE utilizes fused silica capillaries with internal diameters of 20-100 m and lengths varying from 27-100 cm. Constant voltage of up to 30 KV is applied across the ends of the capillary, providing the pump to move the ionic materials. Components move inside the capillaries by the net value of electrophoretic mobility and a process called electroosmotic flow, which has to do with the electrical double layer at the capillary surface and movement of bulk electrolyte towards the cathode. The two most important factors of any separation technique are resolution and reproducibility. Our early work with free zone electrophoresis showed that low pH (2.5) phosphate buffers (0.1 M) containing a polymeric additive (0.05 % hydroxypropylmethyl-cellulose) provided good resolution and reproducibility. Modifications of this buffer with the zwitter ionic detergent, lauryl-sulfobetain and/or acetonitrile led to improved resolution over other methods. Rinsing the capillaries with phosphoric acid yielded better reproducibility than previous methods. Excellent separation of glutenins, gliadins, and gliadin fractions by free zone electrophoresis has been achieved on `27 cm x 20 m' i.d. capillaries in less than 20 min. The relative standard deviation of gliadins ranged from 0.1 to 0.2 %. Size based separations by HPCE are possible with the use of polyacrylamide sieving solutions. Werner et al. (Cereal Chem 71:397 1994) reported the use of `Prosort' by Applied Biosystems, a commercial sieving solution, for gluten proteins, stating that HMW-GS could be separated, but not identified, using this method without improvements in reproducibility and resolution. Other electrophoretic techniques have been adapted for HPCE including IEF and 2-D analyses.

Area quantification of proteins by high performance capillary electrophoresis.

Wheat proteins are known as the major determinate in bread making quality. Therefore, a wide variety of analytical techniques have been used to separate them; the most prevalent being PAGE and HPLC. HPCE was introduced for separating wheat proteins by researchers at Beckman Instruments Inc in 1992. Many research groups have used HPCE for wheat protein studies. A major focus of several of these studies involves quantifying the area of separated proteins in attempts to relate relative areas of specific proteins to quality parameters. Because proteins migrate through capillaries under the influence of an electric field in HPCE, movement is dependent on the charge on the proteins. Thus, proteins with different charges move at different velocities and, therefore, spend different amounts of time in the detector path of capillaries. This directly influences the width of peaks and thereby the area under the peak. Therefore, raw peak areas cannot be used in HPCE for area quantification. To correct for this, peak areas must be divided by migration time. This corrects for peaks with different velocities and allows for comparisons of peak areas from proteins with different migration times. Caution must be used in interpreting data and conclusions from studies based on area quantification of proteins via HPCE that do not explicitly state the use of corrected migration areas. (Abstract of review paper)

Ultrastructure of developing hard and soft red winter wheats after air- and freeze-drying.

Field-grown HRWW Karl and SRWW Clark were harvested at 15, 18, 21, 23, 25, 28, and 35 days after flowering. Wheat was dried by either air-drying in the spike at 28 C or freeze-dried following freezing in liquid nitrogen. The dried wheat was prepared for microscopy. Fresh samples of Karl and Clark also were harvested on the above days and prepared immediately for light and transmission electron microscopy. The method of drying greatly affected cellular ultrastructure. The most pronounced change upon air-drying of developing samples was disappearance of individual protein bodies and conversion of the cytoplasm into a matrix-like material similar to storage protein matrix in mature wheat endosperm. Freeze-dried wheats maintained near-natural ultrastructure, but exhibited various amounts of freeze damage. Conversion of protein bodies to matrix protein was not observed in freeze-dried samples. The results suggest that hardness develops as a result of endosperm senescence rather than accumulation of particular grain components. Senescence may cause changes in the starch granule surface such that surrounding components bind tightly in hard wheats, whereas the binding is weaker in soft wheats. Therefore, the surface of starch granules might be more important than components to which the starch granules bind in determining hardness.

Development of an automated digital image analysis system for the study of starch size distributions in wheat: the use of latex spheres for calibrating errors associated with magnification.

Determining size distributions of wheat starch encompasses the measurement of particles that range in size from less than one [micro]m to over 35 [micro]m in diameter. Quantitative image analysis is a method that yields large amounts of data on individual starch granules. High magnifications are required in order to measure the small starch granules. The high magnifications used reduce the probability large granules will be counted, however. This study was undertaken to estimate the amount of error associated with counting the large type A starch granules in comparison to small granules at two different magnifications. Two analytical-grade sizes of latex spheres (5 and 25 [micro]m) were mixed in a 1:1 concentration as determined by use of a hemacytometer. The spheres were then counted using an image analyzer at two magnifications (10X and 25X objectives). Analysis indicated that use of the 10X objective underestimated the number of 25 [micro]m spheres by 8 %. Use of the 25X objective resulted in undercounting the large latex spheres being by 26 %. This information will be utilized in developing an automated image analysis protocol for determining starch size distributions.

Determining endosperm texture of developing hard and soft red winter wheats dried by different methods using the Single Kernel Wheat Characterization System.

Field-grown hard (Pioneer 2163, Arkan, Karl, Newton, Tam 107, and Tam 200) and soft (Caldwell and Clark) red winter wheats were harvested at 15, 18, 21, 23, 25, 28, and 35 days after flowering. Wheat was dried by a variety of methods: air-dried in the head at 28 C; oven-dried in the head at 40 C; freeze-dried following freezing and threshing in liquid nitrogen; field-dried mature wheat; and freeze-thawed/air-dried where samples were first frozen in liquid nitrogen, thawed at room temperature, and then air-dried at 28 C. The U.S. Grain Marketing Single Kernel Wheat Characterization System was used to measure various grain parameters including the hardness of individual grains. Air-dried and oven-dried samples generally had similar hardness values when compared to mature samples. Soft wheats also were softer than hard samples when dried by these two methods. Freeze-dried grains all had similar, very low values of hardness for samples harvested between 15 and 28 days after flowering, but mature grains 35 days after flowering had normal hardness values. Freeze-thawed samples had hardness values slightly higher than either air- or oven-dried wheats.

Changes in cereal testing and product quality evaluation methodologies at the turn of the century.

Many issues directly affecting cereal science and technology and also processing of cereal products have been arising on a global scale. These issues include food safety, nutritional labeling, integrated pest management, environmental protection, and occupational safety and health. A rapid advance in computer technology will be one of the most important vehicles to adapt the necessary changes in testing methodologies at the turn of the century. Main key words in changing methods are speed, accuracy, safety, environmental friendliness, and objectivity. Some examples of changing methodologies include the Leco N2 Analyzer for protein contents; capillary zone electrophoresis (described above) for protein characterization; supercritical fluid extraction for fats, nutrients, and pesticide residues; solid phase extraction for lipid fractionation on a small scale; digitized imaging for bread loaf sizes and crumb grains, and grains and milled products; NIR for biochemical estimation and quality prediction; and machine-sensing for grain odors.

New methods for extraction of free lipids from wheat flour and their fractionation using supercritical fluid extraction and solid-phase extraction systems.

Environmental concerns, the disposal cost of hazardous waste, and the time required for extraction encouraged us to look for a method to extract lipids from wheat flour that would be faster, less costly, and more environmentally responsible. Free lipids (FL) were extracted from eight wheat samples (1 durum semolina and 7 flours) using a Soxhlet, a Supercritical Fluid Extraction (SFE) system with CO2, and an SFE system with CO2 plus 12.3 mole % ethanol as modifier at 7,500 psi pressure at 80 C chamber temperature with a flow rate of 3 mL/min for 20 min. FL extractability by SFE with CO2 averaged only about 78 % of that by Soxhlet extraction, whereas that by SFE with a modifier averaged 110 %. The extracted FL were fractionated by Solid Phase Extraction (SPE) system and open column silica chromatography (OCSC) with a chloroform-acetone (4:1) mixture, acetone, and methanol as eluting solvents for nonpolar lipids (NL), glycolipids (GL), and phospholipids (PL). The lipid composition expressed as % FL was similar for both SPE and OCSC fractionation methods irrespective of extraction methods. For the FL extracted by SFE with a modifier, NL ranged from 62.3 to 78.4 % by SPE and 63.2 to 81.5 % by OCSC; GL from 11.2 to 32.5 % by SPE and 12.0 to 30.1 % by OCSC and PL from 5.2 to 11.0 % by SPE and 5.4 to 7.6 % by OCSC. Lipid extraction was replicated 4 times and each fractionation by SPE and OCSC was duplicated, giving very high reproducibility. We used a 1-gram cartridge (bonded phase silica) and a total 56 ml of solvents for SPE and 5-gram silica and 165 ml of solvents for OCSC methods. Fractionation could be done for 12 samples/hr by SPE and six samples/5 hr by OCSC.
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