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GrainGenes Sequence Report: NC_011134_131.cds

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Sequence
NC_011134_131.cds
Structure From Source
NC_011134
Source Exons
12421
Gene
clpC
Gene Product
ATP-dependent Clp protease ATP-binding subunit
Remark
CDS note: similar to ref|YP_603351.1| Negative regulator of genetic competence clpC/mecB [Streptococcus pyogenes MGAS10750]; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with dnaK, dnaJ and grpE. Acts before dnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of clpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by dnaK.
DB_xref: GI:195977287
DB_xref: GeneID:6760924
Feature: CDS: locus_tag = 'Sez_0140'; transl_table = 11; protein_id = 'YP_002122531.1';
Codon Start
1

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