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GrainGenes Reference Report: HER-73-198

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Reference	HER-73-198
Title	Missing markers when estimating quantitative trait loci using regression mapping
Journal	Heredity
Year	1994
Volume	73
Pages	198-206
Author	Martinez O Curnow R
Abstract	When using molecular markers to estimate the locations and sizes of effects of QTLs in plant populations a common problem is the loss of marker genotypes for many individuals Here we present a method that uses the information from individuals with missing marker genotypes when fitting regression mapping models using two or three neighbouring markers The approach uses other nearby markers to recover information from the individuals with missing markers The method is presented in detail for the two markers regression mapping technique applied to backcross or double haploid populations The method is exemplified with a simulated data set and with data on a quantitative character in double haploid lines of barley Generalizations of the method to three markers regression mapping models and to F2 populations are outlined.
Keyword	estimation [ Show all 9 ]

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