GrainGenes Reference Report: GEN-138-963
Reference
GEN-138-963
Title
Emperical threshold values for quantitative trait mapping
Journal
Genetics
Year
1994
Volume
138
Pages
963-971
Author
Churchill G Doerge R
Abstract
The detection of genes that control quantitative characters is a problem of great interest to the genetic mapping community Methods for locating these quantitative trait loci (QTL) relative to maps of genetic markers are now widely used This paper addresses an issue common to all QTL mapping methods, that of determining an appropriate threshold value for declaring significant QTL effects An empirical method is described, based on the concept of a permutation test, for estimating threshold values that are tailored to the experimental data at hand The method is demonstrated using two real data sets derived from F2 and recombinant inbred plant populations An example using simulated data from a backcross design illustrates the effect of marker density on threshold values
Keyword
gene-mapping loci oryza sativa plants quantitative-traits
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Reference Report: GEN-138-963
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||