GrainGenes Reference Report: TPJ-89-764
Reference
TPJ-89-764
Title
Copy number variations of CBF genes at the Fr-A2 locus are essential components of winter hardiness in wheat
Journal
The Plant Journal
Year
2017
Volume
89
Pages
764-773
Author
Wurschum T Longin CFH Hahn V Tucker MR Leiser WL
Abstract
Winter hardiness is important for the adaptation of wheat to the harsh winter conditions in temperate regions and is thus also an important breeding goal. Here, we employed a panel of 407 European winter wheat cultivars to dissect the genetic architecture of winter hardiness. We show that copy number variation (CNV) of CBF (C-repeat Binding Factor) genes at the Fr-A2 locus is the essential component for winter survival, with CBF-A14 CNV being the most likely causal polymorphism, accounting for 24.3% of the genotypic variance. Genome-wide association mapping identified several markers in the Fr-A2 chromosomal region, which even after accounting for the effects of CBF-A14 copy number explained approximately 15% of the genotypic variance. This suggests that additional, as yet undiscovered, polymorphisms are present at the Fr-A2 locus. Furthermore, CNV of Vrn-A1 explained an additional 3.0% of the genotypic variance. The allele frequencies of all loci associated with winter hardiness were found to show geographic patterns consistent with their role in adaptation. Collectively, our results from the candidate gene analysis, association mapping and genome-wide prediction show that winter hardiness in wheat is a quantitative trait, but with a major contribution of the Fr-A2 locus.
External Databases
DOI: 10.1111/tpj.13424
Gene Class
Frost resistance
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Reference Report: TPJ-89-764
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||