Query (optional)   in Class  All Allele Author Colleague Collection Assembly Gene Gene Class Gene Product Germplasm Image Journal Keyword Library Locus Map Map Data Marker Pathology Polymorphism Probe Protein QTL Rearrangement Reference Sequence Species Trait Trait Study Two Point Data  

---

GrainGenes Reference Report: NGN-51-885

[Submit comment/correction]

Reference	NGN-51-885
Title	Durum wheat genome highlights past domestication signatures and future improvement targets
Journal	Nature Genetics
Year	2019
Volume	51
Pages	885-895
Author	Maccaferri M [ Show all 68 ]
Abstract	The domestication of wild emmer wheat led to the selection of modern durum wheat, grown mainly for pasta production. We describe the 10.45 gigabase (Gb) assembly of the genome of durum wheat cultivar Svevo. The assembly enabled genome-wide genetic diversity analyses revealing the changes imposed by thousands of years of empirical selection and breeding. Regions exhibiting strong signatures of genetic divergence associated with domestication and breeding were widespread in the genome with several major diversity losses in the pericentromeric regions. A locus on chromosome 5B carries a gene encoding a metal transporter (TdHMA3-B1) with a non-functional variant causing high accumulation of cadmium in grain. The high-cadmium allele, widespread among durum cultivars but undetected in wild emmer accessions, increased in frequency from domesticated emmer to modern durum wheat. The rapid cloning of TdHMA3-B1 rescues a wild beneficial allele and demonstrates the practical use of the Svevo genome for wheat improvement.
Allele	TdHMA3-B1a TdHMA3-B1b
Gene	Cdu1 (Tdurum)
Locus	TRITD5Bv1G197370
Probe	Xusw59 TRITD5Bv1G197370
QTL	QTL0001_CDC-Oladzad-Abbasabadi_et_al__2018 [ Show all 2113 ]
Summarized in	Wiebe K and Pozniak C MAS Wheat. Bringing Genomics to the Wheat Fields. Reduced cadmium concentration MAS Wheat. Marker Assisted Selection in Wheat.

GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.