GrainGenes Reference Report: NAT-491-711
Reference
NAT-491-711
Title
A physical, genetic and functional sequence assembly of the barley genome
Journal
Nature
Year
2012
Volume
491
Pages
711-716
Author
IBSC
Abstract
Barley (Hordeum vulgare L.) is among the worlds earliest domesticated and most important crop plants. It is diploid with a large haploid genome of 5.1 gigabases (Gb). Here we present an integrated and ordered physical, genetic and functional sequence resource that describes the barley gene-space in a structured whole-genome context. We developed a physical map of 4.98 Gb, with more than 3.90 Gb anchored to a high-resolution genetic map. Projecting a deep whole-genome shotgun assembly, complementary DNA and deep RNA sequence data onto this framework supports 79,379 transcript clusters, including 26,159 high-confidence genes with homology support from other plant genomes. Abundant alternative splicing, premature termination codons and novel transcriptionally active regions suggest that post-transcriptional processing forms an important regulatory layer. Survey sequences from diverse accessions reveal a landscape of extensive single-nucleotide variation. Our data provide a platform for both genome-assisted research and enabling contemporary crop improvement.
Map Data
Barley_2012_AC3_genes
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Reference Report: NAT-491-711
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||