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GrainGenes Reference Report: PMP-55-69

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Reference
PMP-55-69
Title
A homologue of a gene implicated in the virulence of human fungal diseases is present in a plant fungal pathogen and is expressed during infection
Journal
Physiological and Molecular Plant Pathology
Year
1999
Volume
55
Pages
69-73
Author
Hall N
Keon JPR
Hargreaves JA
Abstract
Summary: The gene encoding SnodProt1 (SP1), an extracellular protein secreted by the wheat fungal pathogen, Stagonospora (Septoria) nodorum, has been isolated and characterised. The deduced amino acid sequence exhibits significant similarity to antigenic and allergenic proteins encoded by genes cloned from the human fungal pathogens, Coccidioides immitis and Aspergillus fumigatus, respectively. SP1 also exhibits similarity to an EST cDNA derived from the rice blast fungus, Magnaporthe grisea, grown on isolated rice cell walls. Northern and Western blot analyses show that the gene encoding SP1 is expressed and that the protein is secreted during infection of wheat leaves
Keyword
cell wall
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