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GrainGenes Reference Report: NAR-32-3546

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Reference
NAR-32-3546
Title
Demarcating gene-rich regions of the wheat genome.
Journal
Nucleic Acids Research
Year
2004
Volume
32
Pages
3546-3565
Author
Erayman M
[ Show all 6 ]
Abstract
By physically mapping 3025 loci including 252 phenotypically characterized genes and 17 quantitative trait loci (QTLs) relative to 334 deletion breakpoints, we localized the gene-contai ning fraction to 29% of the wheat genome present as 18 major and 30 minor gene-rich regions (GRRs). The GRRs varied both in gene number and density. The five largest GRRs physically spanning <3% of the genome contained 26% of the wheat genes. Approximate size of the GRRs ranged from 3 to 71 Mb. Recombination mainly occurred in the GRRs. Various GRRs varied as much as 128-fold for gene density and 140-fold for recombination rates. Except for a general suppression in 25-40% of the chromosomal region around centromeres, no correlation of recombination was observed with the gene density, the size, or chromosomal location of GRRs. More than 30% of the wheat genes are in recombination-poor regions thus are inaccessible to map-based cloning.
External Databases
Pubmed: 15240829
https://doi.org/10.1093/nar/gkh639
Map Data
Wheat, Branched spike gene, 2009
Keyword
[ Hide all but 1 of 19 ]
a1-sh2 interval
chromosomal location
cloning
common wheat
density
gene
gene density
genome
grass genomes
linkage map
locus
molecular characterization
physical map
quantitative trait loci
recombination
recombination rates
sequence
suppression
triticum aestivum

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