GrainGenes Reference Report: MGG-216-183
Reference
MGG-216-183
Title
Multiple genes are transcribed in Hordeum-vulgare and Zea-mays that carry the DNA binding domain of the MYB oncoproteins
Journal
Molecular and General Genetics
Year
1989
Volume
216
Pages
183-187
Author
[ Hide all but 1 of 7 ] Marocco A Wissenbach M Becker D Paz-Ares J Saedler H Salamini F Rohde W
Abstract
cDNA clones were isolated from tissue specific cDNA libraries of barley and maize using as a probe the cDNA of the maize gene C1, a regulator of anthrocyanin gene expression. C1-related homology for all of the four cDNAs characterized by sequence analysis is restricted to the N-terminal 120 amino acids of the putative proteins. This region show striking homology to the N-proximal domain of the myb oncoproteins from vertebrates and invertebrates. Within the myb proto-oncogene family this part of the respective gene products functions as a DNA binding domain. Acidic domains are present in the C-proximal protein segments. Conservation of these sequences, together with the genetically defined regulator function of the C1 gene product, suggest that myb-related plant genes code for trans-acting factors which regulate gene expression in a given biosynthetic pathway.
Probe
c-myb.Hv1 c-myb.Hv33
Keyword
Gene expression Invertebrates Regulation Trans-acting factors Vertebrates
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Reference Report: MGG-216-183
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||