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GrainGenes Reference Report: GRC-77-95

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Reference	GRC-77-95
Title	Multi-trait QTL mapping in barley using multivariate regression
Journal	Genetical Research
Year	2001
Volume	77
Pages	95-106
Author	Hackett CA Meyer RC Thomas WTB
Abstract	Summary: Many studies of QTL locations record several different traits on the same population, but most analyses look at this information on a trait-by-trait basis. In this paper we show how the regression approach to QTL mapping of Haley & Knott (1992) may be extended to a multi-trait analysis via multivariate regression, easily programmed in statistical packages. A procedure for identifying QTL locations using forward selection and bootstrapping is proposed. The method is applied to examine the locations for QTLs for six yield characters (the number of fertile stems, the grain number of the main stem, the main stem grain weight, the single plant yield, the plot yield and the thousand grain weight) in a doubled haploid population of spring barley. Several chromosomal locations with effects on more than one trait are found. The method is also suitable for examining a single trait measured in different years or environments, and is used here to examine data on heading date, a highly heritable trait, and plot yield, a trait with moderate heritability and showing QTL-environment interactions
External Databases	Pubmed: 11279835
Keyword	[ Hide all but 1 of 33 ] barley chromosomal location doubled haploid doubled haploid population environment fertile flanking markers grain number grain weight haploid heading heading date heritability hordeum vulgare loci major genes mapping method population powdery mildew resistance qtl qtl mapping quality characters quantitatively varying characters record regression selection single spring spring barley stem weight yield

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