Query (optional)   in Class  All Allele Author Colleague Collection Assembly Gene Gene Class Gene Product Germplasm Image Journal Keyword Library Locus Map Map Data Marker Pathology Polymorphism Probe Protein QTL Rearrangement Reference Sequence Species Trait Trait Study Two Point Data  

---

GrainGenes Reference Report: NCB-7:1001

[Submit comment/correction]

Reference	NCB-7:1001
Title	Improving wheat grain composition for human health by constructing a QTL atlas for essential minerals.
Journal	Communications Biology
Year	2024
Volume	7
Author	[ Hide all but 1 of 18 ] Sigalas PP Shewry PR Riche A Wingen L Feng C Siluveru A Chayut N Burridge A Uauy C Castle M Parmar S Philp C Steele D Orford S Leverington-Waite M Cheng S Griffiths S Hawkesford MJ
Abstract	Wheat is an important source of minerals for human nutrition and increasing grain mineral content can contribute to reducing mineral deficiencies. Here, we identify QTLs for mineral micronutrients in grain of wheat by determining the contents of six minerals in a total of eleven sample sets of three biparental populations from crosses between A.E. Watkins landraces and cv. Paragon. Twenty-three of the QTLs are mapped in two or more sample sets, with LOD scores above five in at least one set with the increasing alleles for sixteen of the QTLs being present in the landraces and seven in Paragon. Of these QTLs, the number for each mineral varies between three and five and they are located on 14 of the 21 chromosomes, with clusters on chromosomes 5A (four), 6A (three), and 7A (three). The gene content within 5 megabases of DNA on either side of the marker for the QTL with the highest LOD score is determined and the gene responsible for the strongest QTL (chromosome 5A for Ca) identified as an ATPase transporter gene (TraesCS5A02G543300) using mutagenesis. The identification of these QTLs, together with associated SNP markers and candidate genes, will facilitate the improvement of grain nutritional quality.
External Databases	https://doi.org/10.1038/s42003-024-06692-7

GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.