Query (optional)   in Class  All Allele Author Colleague Collection Assembly Gene Gene Class Gene Product Germplasm Image Journal Keyword Library Locus Map Map Data Marker Pathology Polymorphism Probe Protein QTL Rearrangement Reference Sequence Species Trait Trait Study Two Point Data  

---

GrainGenes Reference Report: SCI-2020-Wang

[Submit comment/correction]

Reference	SCI-2020-Wang
Title	Horizontal gene transfer of Fhb7 from fungus underlies Fusarium head blight resistance in wheat
Journal	Science
Year	2020
Volume	09Apr2020
Author	Wang H [ Show all 42 ]
Abstract	Fusarium head blight (FHB), a fungal disease caused by Fusarium species that produce food toxins, currently devastates wheat production worldwide, yet few resistance resources have been discovered in wheat germplasm. Here, we cloned the FHB resistance gene Fhb7 based on assembling the genome of Thinopyrum elongatum, a species used in wheat distant hybridization breeding. Fhb7 encodes a glutathione S-transferase (GST) and confers broad resistance to Fusarium species by detoxifying trichothecenes via de-epoxidation. Fhb7 GST homologs are absent in plants, and our evidence supports Th. elongatum has gained Fhb7 via horizontal gene transfer (HGT) from an endophytic Epichloe species. Fhb7 introgressions in wheat confers resistance to both FHB and crown rot in diverse wheat backgrounds without yield penalty, providing a solution for Fusarium resistance breeding.
External Databases	https://doi.org/10.1126/science.aba5435
Gene	Fhb7 (Triticum)
Locus	[ Hide all but 1 of 24 ] Tel7E01T1020600.1 XsdauK130 SdauK66 XsdauK68 XsdauK69 XsdauK70 XsdauK72 XsdauK73 XsdauK74 XsdauK75 XsdauK76 XsdauK77 XsdauK78 XsdauK79 XsdauK80 XsdauK81 XsdauK82 XsdauK83 XsdauK84 XsdauK85 XsdauK86 XsdauK88 XsdauK87 sdauk67
Map Data	Wheat_Fhb7_2020
Probe	SDAUK130 [ Show all 24 ]

GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.