GrainGenes Reference Report: ACD-20-125
Reference
ACD-20-125
Title
The role of knox genes in plant development
Journal
Annual Review of Cell and Developmental Biology
Year
2004
Volume
20
Pages
125-151
Remark
Discusses transcription factor / regulator : HB-KNOX
Author
[ Hide all but 1 of 6 ] Hake S Smith HM Holtan H Magnani E Mele G Ramirez J
Abstract
knox genes encode homeodomain-containing transcription factors that are required for meristem maintenance and proper patterning of organ initiation. In plants with simple leaves, knox genes are expressed exclusively in the meristem and stem, but in dissected leaves, they are also expressed in leaf primordia, suggesting that they may play a role in the diversity of leaf form. This hypothesis is supported by the intriguing phenotypes found in gain-of-function mutations where knox gene misexpression affects leaf and petal shape. Similar phenotypes are also found in recessive mutations of genes that function to negatively regulate knox genes. KNOX proteins function as heterodimers with other homeodomains in the TALE superclass. The gibberellin and lignin biosynthetic pathways are known to be negatively regulated by KNOX proteins, which results in indeterminate cell fates.
External Databases
https://www.ncbi.nlm.nih.gov/pubmed/15473837
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Reference Report: ACD-20-125
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||