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GrainGenes Reference Report: SCI-287-303

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Reference
SCI-287-303
Title
Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
Journal
Science
Year
2000
Volume
287
Pages
303-305
Author
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Ye X
Al Babili S
Kloti A
Zhang J
Lucca P
Beyer P
Potrykus I
Abstract
Summary: Rice (Oryza sativa), a major staple food, is usually milled to remove the oil-rich aleurone layer that turns rancid upon storage, especially in tropical areas. The remaining edible part of rice grains, the endosperm, lacks several essential nutrients, such as provitamin A. Thus, predominant rice consumption promotes vitamin A deficiency, a serious public health problem in at least 26 countries, including highly populated areas of Asia, Africa, and Latin America. Recombinant DNA technology was used to improve its nutritional value in this respect. A combination of transgenes enabled biosynthesis of provitamin A in the endosperm
Keyword
aleurone layer
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