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GrainGenes Reference Report: PNA-96-10922

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Reference	PNA-96-10922
Title	The small GTP-binding protein Rac is a regulator of cell death in plants
Journal	Proceedings of the National Academy of Sciences, USA
Year	1999
Volume	96
Pages	10922-10926
Author	Kawasaki T [ Show all 7 ]
Abstract	Summary: Cell death plays important roles in the development and defense of plants as in other multicellular organisms. Rapid production of reactive oxygen species often is associated with plant defense against pathogens, but their molecular mechanisms are not known. We introduced the constitutively active and the dominant negative forms of the small GTP-binding protein OsRac1, a rice homolog of human Rac, into the wild type and a lesion mimic mutant of rice and analyzed H2O2 production and cell death in transformed cell cultures and plants. The results indicate that Rac is a regulator of reactive oxygen species production as well as cell death in rice
Keyword	[ Hide all but 1 of 34 ] amino acid sequence apoptosis binding proteins cell cell culture cell death complementary dna culture cytotoxicity death defense defense mechanisms dominant experimental infections fungal diseases gtp binding gtp binding protein guanosine triphosphate h2o2 human hydrogen peroxide magnaporthe grisea mechanism molecular mechanism mutant oryza sativa oxygen pathogen plant defense reactive oxygen species regulation rice transgenic plant wild

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