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GrainGenes Reference Report: PLC-14-3191

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Reference	PLC-14-3191
Title	Gibberellin-mediated proteasome-dependent degradation of the barley DELLA protein SLN1 repressor
Journal	Plant Cell
Year	2002
Volume	14
Pages	3191-3200
Author	Fu XD [ Show all 7 ]
Abstract	Summary: DELLA proteins are nuclear repressors of plant gibberellin (GA) responses. Here, we investigate the properties of SLN1, a DELLA protein from barley that is destabilized by GA treatment. Using specific inhibitors of proteasome function, we show that proteasome-mediated protein degradation is necessary for GA-mediated destabilization of SLN1. We also show that GA responses, such as the aleurone alpha-amylase response and seedling leaf extension growth, require proteasome-dependent GA-mediated SLN1 destabilization. In further experiments with protein kinase and protein phosphatase inhibitors, we identify two additional signaling steps that are necessary for GA response and for GA-mediated destabilization of SLN1. Thus, GA signaling involves protein phosphorylation and dephosphorylation steps and promotes the derepression of GA responses via proteasome-dependent destabilization of DELLA repressors
External Databases	Pubmed: 12468736
Keyword	[ Hide all but 1 of 25 ] abscisic acid aleurone aleurone protoplasts alpha-amylase arabidopsis thaliana barley cereal aleurone degradation extension gene expression gibberellin growth hordeum vulgare hormonal-regulation kinase phosphatase phosphorylation plasma membrane protein protein degradation protein kinase responses signal transduction signaling slender mutant

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